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. 1983 Oct;50(2):175–180.

Gastrointestinal uptake and blood clearance of antigen in the presence of IgA antibodies.

T Skogh, L Edebo, O Stendahl
PMCID: PMC1454329  PMID: 6194104

Abstract

In selected experiments, IgA antibodies with specificity for dinitrophenyl (DNP) groups appeared to prevent gastrointestinal passage of antigenic fragments of DNP-conjugated protein given orally to mice. The antigen did not, however, pass across the gut as an intact macromolecule even in control animals. IgA was not found to increase the blood clearance of DNP-conjugated protein given intravenously and it is concluded that IgA probably does not have any important role in mediating elimination of macromolecular antigens from the blood.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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