Table I. STAT3 phosphorylation after stimulation with CLC purified from lysate correlates with expression of membrane CNTFR.
Tissue origin | Cell line | CNTFR expression | STAT3 phosphorylation after cytokine stimulation |
|||
---|---|---|---|---|---|---|
None | LIF | CNTF | CLC | |||
Neuroblastoma | SK-N-MC | + | – | + | + | + |
SK-N-GP | + | – | + | + | + | |
SK-N-SH | + | – | + | + | + | |
IMR32 | + | – | + | + | + | |
Glioblastoma | T98G | – | – | + | – | – |
A172 | – | – | + | – | – | |
CCF-STTG1 | – | – | + | – | – | |
Epidermoid carcinoma | KB | – | – | + | – | – |
Hepatoma | HepG2 | – | – | + | – | – |