Table 1.

Linear dynamic range, correlation cofficients (r²) and limits of detections (LODs) of the LC/APCI-MS/MS method for the determination of aldehydes as DNPH derivatives^a

Compound	SRM (m/z)	Range (μM)	ab × 10−4	r2	n	LOD (nM)c
MDA	235 → 159	0.004–400	2.96 ± 0.05	0.997	39	1.0
Acrolein	235 → 163	0.003–200	1.55 ± 0.03	0.995	36	1.0
4-HHE	293 → 167	0.003–150	9.22 ± 0.20	0.995	36	0.3
4-HNE	335 → 167	0.003–150	9.14 ± 0.20	0.994	36	0.6
n-hexanal	279 → 163	0.004–350	3.90 ± 0.07	0.997	39	1.0
n-heptanal	293 → 163	0.003–350	3.78 ± 0.08	0.995	39	1.0
n-nonanal	321 → 163	0.003–350	3.70 ± 0.09	0.998	39	1.0

^aCalibration curve: y = ax, forced through zero.

^b± Values are confidence intervals at 95% probability level.

^cLimit of detection (S/N ratio = 3) calculated under SRM conditions.