Figure 6. Dynamic changes in preferred orientation are enhanced by nCRF stimulation.
A, orientation tuning curves of an example cell at Tdev and Tdec at 1 × CRF. Black and grey vertical lines, peak positions of the fitted curve (von Mises distribution) at Tdev and Tdec, respectively. The horizontal arrow indicates shift in the preferred orientation (13.1 deg). Error bar, ±s.e.m.B, tuning curves of the same cell at 4 × CRF. The shift in preferred orientation was 17.6°. C–E, comparison of shifts in preferred orientation between different sizes (C, at 1 × CRF versus that at 2 × CRF; D, at 1 × CRF versus that at 4 × CRF; E, at 2 × CRF versus that at 4 × CRF). The slopes of the robust regression (continuous lines) were 0.69, 0.46 and 0.68 for C, D and E, respectively, which were significantly different from zero (all P < 10−10). Significant changes in preferred orientations over time at 1 × CRF (C), 2 × CRF (E) and 4 × CRF (D) are marked as filled points.