TABLE 2.

Deficiency stocks that suppress the overexpression of CBP proteins

GMR-CBP FL		GMR-CBP ΔNZK		GMR-CBP ΔBHQ		GMR-CBP ΔQ
Cytological location	Phenotype	Cytological location	Phenotype	Cytological location	Phenotype	Cytological location	Phenotype
31C1-32E1	Enhancer	3D6-4F5	Enhancer	42E1-44D8	Enhancer
60F1-60F5	Enhancer	7B2-7C1	Enhancer	63F6-64C15	Enhancer
None found		64C1-65C1	Enhancer	10A7-10F7	Enhancer	88F9-89B9	Enhancer
76B4-77B1	Enhancer	13F1-14C1	Enhancer	95D7-95F17	Enhancer
96B6-96D2	Enhancer	15D3-16A6	Enhancer	96F1-97B1	Enhancer
30D1-31F1	Enhancer
48E12-50D7	Enhancer
96F1-97B1	Enhancer
99A1-99B6	Enhancer
53E1-53F11	Suppressor	5C3-6C12	Suppressor	5C3-6C12	Suppressor
76B4-77B1	Suppressor	23C1-23E2	Suppressor	22D2-22F2	Suppressor
60A3-60B7	Suppressor	23C1-23C5	Suppressor
None found		63C2-63F7	Suppressor	23E5-23F5	Suppressor
65D4-65E6	Suppressor	28A4-28D9	Suppressor
71F1-72D10	Suppressor	30C3-30F1	Suppressor
76B6-77A1	Suppressor	54F2-56A1	Suppressor
						76B4-77B1	Suppressor

We were unable to refine the genetic maps for several genomic regions. This may be due to the lack of available mutations for all predicted genes or the modifying activity may be the product of simultaneously removing two or more genes. Note that stocks carrying deletions of the 76B4-77B1 interval enhance the rough-eye phenotype of GMR-CBP ΔNZK but suppress the phenotype of GMR-CBP ΔBHQ and GMR-CBP ΔQ. Also note that deletions of the 5C3-6C12 region suppress both GMR-CBP ΔBHQ and GMR-CBP ΔQ. Additionally, deletions of the 96F1-97B1 interval enhance both GMR-CBP ΔBHQ and GMR-CBP ΔQ. These three regions are likely to harbor genes that interact or are regulated by specific domains of CBP. Deletions that modified more than one construct are underlined.