TABLE 2.

Molecular lesions identified in dTAB2 (CG7417)

Allele	DNA level	Protein level
G71	CAG → TAG	Gln40 → Stop
G576	CAG → TAG	Gln66 → Stop
G973	CAG → TAG	Gln107 → Stop
G58	CAA → TAA	Gln119 → Stop
G635	CGA → TGA	Arg209 → Stop
G609	CAA → TAA	Gln216 → Stop
G421	CAG → TAG	Gln224 → Stop
G867	CGA → TGA	Arg233 → Stop
G503 (independent of G585)	CAA → TAA	Gln317 → Stop
G585 (independent of G503)	CAA → TAA	Gln317 → Stop
G683	CAG → TAG	Gln330 → Stop
G245	7-bp Del bp 1203–1209 of CDS	Premature Stop at AA422
G666	CAG → TAG	Gln458 → Stop
G552 (independent of G734)	CAG → TAG	Gln486 → Stop
G734 (independent of G552)	CAG → TAG	Gln486 → Stop
G642	5′ splice site intron 2 GT → GA	—
G788	CAG → TAG	Gln542 → Stop
G253	CAG → TAG	Gln544 → Stop
G981	CTG → CAG + GAC → AAC	Leu570 → Gln + Asp592 → Asn
G539	284-bp Del bp 1711–1994 of CDS +CA insertion at breakpoint → in frame!	Thr571 → His, Glu572 → Gln, AA 573–666 deleted
G275	AGA → TGA	Arg581 → Stop
G933	3′ splice site intron 3 AG → AA	—
G746	CAA → TAA	Gln633 → Stop
G489	CAG → TAG	Gln634 → Stop
G548	CAG → TAG	Gln641 → Stop
G954	CAG → TAG	Gln689 → Stop
G545	CAG → TAG	Gln712 → Stop
G227	CAG → TAG	Gln713 → Stop
G812	CAG → TAG	Gln720 → Stop
G271	CAG → TAG	Gln728 → Stop
G829	CAG → TAG	Gln731 → Stop
G603	CAG → TAG	Gln744 → Stop
G520 (independent of G715)	TGG → TAG	Trp767 → Stop
G715 (independent of G520)	TGG → TAG	Trp767 → Stop
G701 (independent of G824)	TGG → TGA	Trp767 → Stop
G824 (independent of G701)	TGG → TGA	Trp767 → Stop
G211	TGC → GGC + AAC → AAA	Cys769 → Gly + Asn770 → Cys
G928	GGT → GAT	Gly794 → Asp
G825	53-bp Del bp 2437–2489 of CDS	Frameshift leads to a longer protein

Alleles are ordered according to their position in the protein. Nucleotide changes are in boldface type. In a GMR-Gal4 UAS-egr background, all alleles display an “intermediate” strength of suppression.