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. 2005 Dec;171(4):1729–1739. doi: 10.1534/genetics.105.041947

TABLE 1.

Estimates of the neutral mutation and recombination parameters for seven genes located on the third chromosome of Drosophila pseudoobscura

Arr en exu1 eve Mef2 Amy1 vg F6
AR n 39 45 40 32 43 42 37
    Θ 5.6 ± 3.1 1.0 ± 0.8 1.6 ± 1.7 1.6 ± 1.0 3.2 ± 1.7 3.8 ± 2.0 4.0 ± 2.6
    C 28.5 >10,000 0.4 >10,000 229.2 72.0 21.1
    C95 4.8–36.5 ND 0.04–61.1 ND 3.2–129.8 2.2–78.4 0.9–28.4
    c 5.0 ND 0.2 ND 72.2 18.9 5.3
PP n 20 21 21 21 24 20 18
    Θ 5.1 ± 2.9 0.7 ± 0.9 3.4 ± 2.1 3.9 ± 2.3 0.7 ± 0.6 5.8 ± 5.4 4.2 ± 3.3
    C 27.7 1.6 31.9 40.2 >10,000 <0.5 4.8
    C95 2.5–49.3 1.0–4.0 1.8–55.7 1.2–55.5 ND ND 0.6–18.0
    c 5.4 2.4 9.3 10.3 ND ND 1.2
ST n 16 15 16 13 17 16 16
    Θ 5.8 ± 3.7 1.7 ± 1.0 0.1 ± 0.3 1.2 ± 1.8 2.9 ± 2.5 8.0 ± 4.2 3.0 ± 2.3
    C 13.2 474.6 >10,000 <0.5 4.4 36.1 11.8
    C95 1.7–32.4 2.4–562.5 ND ND 0.6–15.9 5.1–54.5 0.7–36.6
    c 2.3 276.9 ND ND 1.5 4.5 3.9
CH n 16 16 16 15 17 16 14
    Θ 7.2 ± 4.3 1.6 ± 0.9 3.8 ± 2.8 3.8 ± 2.4 2.8 ± 2.4 5.8 ± 8.3 4.2 ± 2.5
    C 17.4 >10,000 10.1 20.2 4.0 <0.5 45.6
    C95 4.3–28.4 ND 0.4–21.7 29.6–495.9 0.6–17.3 ND 1.4–101.1
    c 2.4 ND 2.6 5.4 1.4 ND 10.8
TL n 6 6 6 6 6 6 6
    Θ 4.9 ± 2.8 0.9 ± 0.8 0.0 ± 0.0 5.1 ± 5.9 4.5 ± 3.2 11.7 ± 6.4 2.7 ± 2.1
    C 58.6 32.4 ND <0.5 8.7 37.3 6.6
    C95 6.9–259.3 1.6–32.4 ND ND 0.7–256.8 6.7–74.8 1.7–33.7
    c 12.0 37.4 ND ND 2.0 3.2 2.4
All n 99 105 101 89 109 102 94
    Sites 404 (320) 358 (166) 374 (146) 418 (309) 458 (365) 651 (292) 436 (348)
    S 49 14 25 38 48 80 53
    Θ 6.5 ± 3.4 1.3 ± 1.0 3.5 ± 2.4 5.6 ± 3.7 5.7 ± 3.0 17.0 ± 9.6 5.8 ± 3.7
    C 30.3 152.8 12.7 11.1 34.7 12.7 13.1
    C95 5.3–33.1 1.3–94.6 0.6–13.1 1.3–17.1 2.8–41.3 5.4–18.4 1.6–18.8
    c 4.7 115.6 3.6 2.0 6.1 0.7 2.3

Arr, gene arrangement; n, sample size; Θ, heterozygosity per gene based on the number of segregating sites ± standard error (Watterson 1975); C, estimates of the neutral recombination parameter (Hudson 1987); C95, 95% confidence interval on C determined with bootstrap replication; ND, not determined.