TABLE 1.
Body weight
|
Body weight gain
|
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
21 days
|
42 days
|
63 days
|
21–42 days
|
42–63 days
|
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Chromosome | Effect (g) | SE | P-value | Effect (g) | SE | P-value | Effect (g) | SE | P-value | Effect (g) | SE | P-value | Effect (g) | SE | P-value |
1 | 0.42 | 0.14 | 0.003 | 1.29 | 0.32 | <0.001 | 0.87 | 0.29 | 0.003 | 0.57 | 0.22 | 0.011 | 0.06 | 0.19 | 0.753 |
2 | 0.36 | 0.23 | 0.118 | 1.87 | 0.50 | <0.001 | 2.68 | 0.44 | <0.001 | 1.53 | 0.35 | 0.000 | 1.54 | 0.28 | <0.001 |
3 | 0.80 | 0.16 | <0.001 | 1.48 | 0.34 | <0.001 | 1.12 | 0.32 | <0.001 | 0.44 | 0.24 | 0.067 | 0.12 | 0.20 | 0.560 |
4 | 0.14 | 0.17 | 0.397 | 0.53 | 0.36 | 0.135 | 0.72 | 0.31 | 0.020 | 0.66 | 0.25 | 0.008 | 0.43 | 0.20 | 0.029 |
5 | −0.12 | 0.18 | 0.504 | 1.18 | 0.41 | 0.004 | 1.77 | 0.36 | <0.001 | 0.72 | 0.28 | 0.011 | 1.10 | 0.23 | <0.001 |
6 | 0.27 | 0.11 | 0.012 | 0.73 | 0.23 | 0.002 | 0.15 | 0.22 | 0.489 | 0.33 | 0.16 | 0.040 | −0.19 | 0.14 | 0.159 |
7 | 0.45 | 0.18 | 0.012 | 1.07 | 0.39 | 0.006 | 0.88 | 0.34 | 0.009 | −0.09 | 0.27 | 0.751 | 0.01 | 0.21 | 0.959 |
8 | 0.33 | 0.15 | 0.031 | 0.96 | 0.33 | 0.004 | 0.91 | 0.32 | 0.005 | 0.49 | 0.23 | 0.035 | 0.36 | 0.20 | 0.074 |
9 | −0.22 | 0.15 | 0.137 | 0.22 | 0.33 | 0.511 | 0.18 | 0.29 | 0.545 | 0.24 | 0.23 | 0.293 | 0.13 | 0.19 | 0.471 |
10 | −0.19 | 0.18 | 0.289 | −0.48 | 0.39 | 0.221 | −0.28 | 0.34 | 0.408 | −0.33 | 0.27 | 0.223 | 0.06 | 0.21 | 0.768 |
11 | −0.21 | 0.23 | 0.379 | 1.45 | 0.51 | 0.005 | 1.79 | 0.44 | <0.001 | 1.82 | 0.36 | <0.001 | 0.68 | 0.28 | 0.015 |
12 | 0.12 | 0.14 | 0.386 | 0.36 | 0.31 | 0.245 | 0.20 | 0.28 | 0.469 | 0.12 | 0.22 | 0.592 | 0.04 | 0.18 | 0.841 |
13 | 0.36 | 0.15 | 0.016 | 1.06 | 0.33 | 0.001 | 0.89 | 0.30 | 0.003 | 0.33 | 0.23 | 0.145 | 0.02 | 0.19 | 0.933 |
14 | 0.33 | 0.13 | 0.010 | 0.28 | 0.28 | 0.326 | 0.66 | 0.26 | 0.009 | −0.35 | 0.20 | 0.077 | 0.33 | 0.16 | 0.039 |
15 | 0.48 | 0.14 | <0.001 | 1.37 | 0.31 | <0.001 | 0.90 | 0.31 | 0.004 | 0.67 | 0.21 | 0.002 | 0.14 | 0.19 | 0.483 |
16 | 0.26 | 0.11 | 0.023 | 1.02 | 0.26 | <0.001 | 0.51 | 0.24 | 0.037 | 0.54 | 0.18 | 0.003 | −0.22 | 0.15 | 0.159 |
17 | −0.35 | 0.13 | 0.009 | 0.64 | 0.30 | 0.033 | 1.00 | 0.28 | <0.001 | 1.05 | 0.21 | <0.001 | 0.71 | 0.18 | <0.001 |
18 | 0.22 | 0.12 | 0.069 | 0.62 | 0.26 | 0.019 | 0.24 | 0.25 | 0.335 | 0.19 | 0.18 | 0.298 | 0.00 | 0.16 | 0.991 |
19 | −0.37 | 0.16 | 0.020 | −0.51 | 0.36 | 0.159 | −0.53 | 0.33 | 0.116 | −0.32 | 0.25 | 0.209 | −0.04 | 0.21 | 0.833 |
All | 3.08 | 0.46 | <0.001 | 15.15 | 1.20 | <0.001 | 14.69 | 1.03 | <0.001 | 8.63 | 0.84 | <0.001 | 5.28 | 0.67 | <0.001 |
Y | −0.08 | 0.09 | 0.371 | 0.53 | 0.19 | 0.006 | 0.72 | 0.18 | <0.001 | 0.80 | 0.13 | <0.001 | 0.39 | 0.12 | 0.001 |
The effect is the estimated substitution effect of the DU6i chromosome vs. the DBA/2 chromosome. The P-value is given for the comparison between animals that are carriers of DU6i chromosomes vs. DBA/2 animals. P-values from bootstrapping can be found in supplemental Table 3 at http://www.genetics.org/supplemental/. Significant P-values <0.05 are in italics. SE, standard error.