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. 2006 Jan;172(1):663–686. doi: 10.1534/genetics.105.046417

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Copyright © 2006 by the Genetics Society of America

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Figure 1. — Power curves of the test statistics F_4,ad, F_4,a, F_2,ad, and F_2,a against the disequilibrium coefficient for a dominant mode of inheritance a = d = 1.0 at a 0.05 significance level. F_4,ad and F_4,a are calculated when marker A has four equal frequency alleles; i.e., . The measures of LD are (A and B) and (C and D) . F_2,ad and F_2,a are calculated by collapsing two of the four alleles: (A and C) alleles A₁ and A₂ are collapsed as one allele, and alleles A₃ and A₄ are collapsed to be the other; (B and D) alleles A₁ and A₃ are collapsed to be one allele, and alleles A₂ and A₄ are collapsed to be the other. The other parameters are q₁ = 0.50, h² = 0.25, N = 200.

Inline graphic — Power curves of the test statistics F_4,ad, F_4,a, F_2,ad, and F_2,a against the disequilibrium coefficient for a dominant mode of inheritance a = d = 1.0 at a 0.05 significance level. F_4,ad and F_4,a are calculated when marker A has four equal frequency alleles; i.e., . The measures of LD are (A and B) and (C and D) . F_2,ad and F_2,a are calculated by collapsing two of the four alleles: (A and C) alleles A₁ and A₂ are collapsed as one allele, and alleles A₃ and A₄ are collapsed to be the other; (B and D) alleles A₁ and A₃ are collapsed to be one allele, and alleles A₂ and A₄ are collapsed to be the other. The other parameters are q₁ = 0.50, h² = 0.25, N = 200.