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. 2006 Feb;172(2):1031–1042. doi: 10.1534/genetics.105.050625

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Copyright © 2006 by the Genetics Society of America

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Figure 6. — Animals heterozygous for ion channel mutations interaction with ATPα^DTS1. (A) Heterozygous sei/+, eag/+, Sh/+, and eag Sh/+ + do not show any interaction with ATPα mutants. (B) Heterozygous para allele combinations ts1/+ (diamonds), st109/+ (open squares), and ts115/+ (triangles) with ATPα^DTS1/+ show a significant reduction in life span (P < 0.05). Surprisingly, the para deficiency Df(1)LD34 (circles) did not have any affect on ATPα^DTS1 life span. (C) para^ts1/+;;ATPα^DTS1/+ brain slice at day 16 shows more severe pathology than age-matched para^ts1 or ATPα^DTS1 alone. Each point represents mean survival ±SEM. Bar, 50 μm.