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Gene tree of 18 human CMAH haplotypes when the chimpanzee sequence was used to infer the MRCA sequence. A dot and a tick mark represent a nucleotide substitution and an indel, respectively. Parallel substitutions at 2073 are placed on the branches leading to P and C3. Similarly, parallel substitutions at 1793 are placed on the B2 and B3 terminal branches. The arrow in the tree denotes the exon deletion by AluY insertion.
