TABLE 3.

Hsp70 substrate-binding affinities

	Kdb (μm)
Hsp70 isoforma	ATP	ADP	[PSI+]c
AAA	60.91	7.62	+ + + +
CCC	59.64	4.55	+
PPP	55.34	12.87	NA
CAA	55.59	5.62	+ + +
PAA	51.53	45.43	NA
ACA	67.73	8.93	+ + +
APA	58.21	2.56	+/–
AAC	64.37	12.26	+ + + + +
AAP	53.40	10.06	+ + + + +

^aNames are as described in Table 2 and in the text.

^bK_d was determined by titrating fluorescently labeled peptide with Hsp70.

^cValues from Table 2 are reproduced to make comparison easier.