TABLE 1.
Default population | |
Effective population size | 100 |
No. of generations of random mating since QTL mutation occurred | 100 |
No. of markers genotyped | 10 |
No. of alleles per marker in founder population | 2 |
Initial marker/QTL allele frequencies in founder population | 0.5/0.005 |
Distance (cM) between adjacent markers | 1, 0.5, 0.25 |
Position of QTL | Halfway between markers 5 and 6 |
Additive effect of QTL allele mutation | 1 |
Residual standard deviation | 1 |
No. of individuals (records) in final generation | 100 |
Two-breed cross | |
No. of generations of random mating following the initial cross | 1, 5, 10, 20, 100 |
Initial marker/QTL allele frequencies in founder population | |
Breed 1 | 0.5/0.1, 0.9 |
Breed 2 | 0.5/0.9, 0.1 |
Distance (cM) between adjacent markers | 1 |
Noncentral QTL position | |
Distance (cM) between adjacent markers | 1 |
Position of QTL | Halfway between markers 3 and 4 |
Random founder allele frequencies | |
Initial marker/QTL allele frequencies in founder population | 0.2–0.8/0.005 |
Distance (cM) between adjacent markers | 1 |
Worst-case scenario | |
No. of generations of random mating following the initial cross | 10 |
Initial marker/QTL allele frequencies in founder population | |
Breed 1 | 0.2–0.8/0.1, 0.9 |
Breed 2 | 0.2–0.8/0.9, 0.1 |
Distance (cM) between adjacent markers | 1 |
Position of QTL | Halfway between markers 3 and 4 |
Alternative effective population size | |
Effective population size | 50, 200 |
Distance (cM) between adjacent markers | 1 |
Smaller QTL effect | |
Distance (cM) between adjacent markers | 1 |
Additive effect of QTL allele mutation | 0.5 |
Parameters for alternative populations are the same as the default except for those specified here.