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. 2006 Mar;172(3):1955–1965. doi: 10.1534/genetics.105.048686

TABLE 1.

Parameters for default and alternative simulated populations

Default population
    Effective population size 100
    No. of generations of random mating since QTL mutation occurred 100
    No. of markers genotyped 10
    No. of alleles per marker in founder population 2
    Initial marker/QTL allele frequencies in founder population 0.5/0.005
    Distance (cM) between adjacent markers 1, 0.5, 0.25
    Position of QTL Halfway between markers 5 and 6
    Additive effect of QTL allele mutation 1
    Residual standard deviation 1
    No. of individuals (records) in final generation 100
Two-breed cross
    No. of generations of random mating following the initial cross 1, 5, 10, 20, 100
    Initial marker/QTL allele frequencies in founder population
        Breed 1 0.5/0.1, 0.9
        Breed 2 0.5/0.9, 0.1
    Distance (cM) between adjacent markers 1
Noncentral QTL position
    Distance (cM) between adjacent markers 1
    Position of QTL Halfway between markers 3 and 4
Random founder allele frequencies
    Initial marker/QTL allele frequencies in founder population 0.2–0.8/0.005
    Distance (cM) between adjacent markers 1
Worst-case scenario
    No. of generations of random mating following the initial cross 10
    Initial marker/QTL allele frequencies in founder population
        Breed 1 0.2–0.8/0.1, 0.9
        Breed 2 0.2–0.8/0.9, 0.1
    Distance (cM) between adjacent markers 1
    Position of QTL Halfway between markers 3 and 4
Alternative effective population size
    Effective population size 50, 200
    Distance (cM) between adjacent markers 1
Smaller QTL effect
    Distance (cM) between adjacent markers 1
    Additive effect of QTL allele mutation 0.5

Parameters for alternative populations are the same as the default except for those specified here.