Figure 1.

PMN response of BXD RI mice. Mice were exposed for 4 hr to aerosolized LPS and harvested immediately thereafter. Whole-lung lavage was performed and the fluid assayed for the number of PMNs per milliliter. Mean neutrophil counts for parental strains are indicated by open rectangles. Error bars represent standard deviation (n ≥ 5 mice per strain). BXD29 mice are essentially unresponsive to inhaled LPS.