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Comparison of recombination pathways in E. coli
| Recombination pathway
|
||||
|---|---|---|---|---|
| RecY | RecBCD | RecF | RecE | |
| Operative in genetic background | recD | Wild type | recBC sbcBC | recBC sbcA |
| Helicase | RecBC | RecBCD | RecQ (UvrD, HelD) | — |
| Exonuclease(s) | RecJ, ExoVII, ExoI, ExoX, SbcCD | RecBCD | RecJ | ExoVIII, RecJ |
| Facilitation of strand-exchange protein loading by: | RecBC | RecBCD | RecF, O, R | RecTa |
| Recombinational exchanges focused at: | DNA ends | Chi sites | DNA ends | DNA ends |
RecT is itself a strand-exchange protein.
