Figure 4.

Modifiers that enhance the L mutant phenotype in eye. (A) Overexpression of EP3408, an insertion at pygo in wild-type disc (ey>pygo) causes reduction in eye size. (B) Overexpression of pygo in L²/+ mutant eye disc (L²/+; ey>pygo) enhances the ventral eye loss phenotype to no eye in eye disc (B) and adult eye (C). Overexpression of (D–F) emc using EP415 and (G–I) B using EP1350 in the eye. (D) ey>emc results in a small eye. (E and F) L²/+; ey>emc enhances the L²/+ mutant phenotype to no eye. (G) Overexpression of B in eye (ey>B) strongly reduces the eye size. (H and I) L²/+; ey>emc strongly enhances the L mutant phenotype to no eye.