TABLE 3.
Molecular structure of Lamin C excision alleles
| Mutant name | Coding region | No. of insertions | Insertion size (kb) | GFPa | white+/−b |
|---|---|---|---|---|---|
| G00158 (parent stock) | Intact | 1 | 6 | + | + |
| LamCEX3 | Intact | 1 | 1.5 | — | — |
| LamCEX5 | Intact | 1 | 1.8 | — | — |
| LamCEX16 | Intact | 1 | 1.5 | — | — |
| LamCEX187 | 357-bp deletion in first exon | 2 | ND | + | — |
| LamCEX265 | Intact | 1 | 1.4 | — | — |
| LamCEX296 | 560-bp deletion in first exon | 0 | NA | — | — |
| LamCEX364 | Intact | 1 | ND | + | — |
ND, not done; size exceeded standard PCR. NA, not applicable.
a
Determined by PCR.
b
Determined by eye color phenotype indicating presence of white reporter (+, red; −, white).