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Mutations found in representative suppressors
| Allele | Base substitution | Amino acid replacements |
|---|---|---|
| srb7-1 | G265T | E89a |
| rox3-102 | G405A | W135a |
| sin4-111 | G383A | G128D |
| G1836T | E612D | |
| sin4-133ts | G721A | A241T |
| G1836T | E612D | |
| srb9-9 | 2675: deletion of T | L892YFPLSIDa |
| srb10-27 | 768: deletion of G | M257a |
The E612D amino acid substitution identified in both sin4 alleles was traced back to the parent strain, which is phenotypically SIN4.
Termination codon.
