TABLE 4.
Examples of genes whose expression changed from 32 to 40 hr
| Fold change
|
Experimental group
|
In pupae
|
||||
|---|---|---|---|---|---|---|
| P-value | Twofold | Fivefold | Gene | Comment | ||
| −6.79 | 0.01 | 7 | Yes | No | Inscuteable (insc) | Asymmetric cell division in PNS lineage |
| −5.20 | 0.02 | 5 | Yes | No | scute (sc) | Transcription factor, bristle sense organ |
| −3.17 | 0.03 | No | No | non-stop (not) | Ubiquitin hydrolase, eye planar polarity | |
| −3.08 | 0.05 | No | No | TNF-receptor-associated factor 1 (Traf1) | Upstream of Jnk pathway and msn | |
| −2.98 | 0.01 | Yes | No | sugarless (sgl) | UDP-glucose 6-dehydrogenase, signaling | |
| −2.91 | 0.04 | No | No | Cyclin A (CycA) | Cell division | |
| −2.53 | 0.02 | No | No | Beadex (Bx) | Transcription factor, wing scalloping | |
| −2.52 | 0.01 | No | No | twine | Protein tyrosine phosphatase, cell division | |
| −2.35 | 0.01 | No | No | wingless (wg) | Wnt ligand, wing growth | |
| −2.30 | 0.04 | No | No | Ubiquitin C-terminal hydrolase (Uch-L3) | Ubiquitin hydrolase | |
| −2.27 | 0.03 | Yes | No | Cyclin B (CycB) | Cell division | |
| −2.04 | 0.03 | No | No | inturned (in) | Planar polarity | |
| 2.37 | 0.03 | 3 | No | No | quail (qua) | Gelsolin/villin, actin bundling, female sterile |
| 3.10 | 0.00 | Yes | No | CG11546 | Drosophila Kermit, planar polarity | |
| 3.12 | 0.00 | No | No | Rala | Ras family GTPase, hairs and bristles | |
| 3.95 | 0.03 | Yes | No | forked (f) | Actin bundling, twisted bristles and hairs | |
| 3.95 | 0.04 | Yes | No | Ecdysone receptor (EcR) | Nuclear receptor, wing phenotype | |
| 4.94 | 0.02 | Yes | No | krotzkopf verkehrt (kkv) | Blimp embryonic cuticle phenotype | |
| 5.25 | 0.01 | 2 | No | No | Ecdysone-induced protein 71CD | |
| 5.55 | 0.00 | 2 | Yes | No | karst (kst) | Heavy β-spectrin, wing phenotype |
| 6.24 | 0.01 | 2 | No | No | furrowed (fw) | Bristles, notum, and wing phenotypes |
| 6.43 | 0.01 | 2 | No | No | jbug | Filamen |
| 6.51 | 0.00 | 2 | No | No | yellow-d2 | Related to yellow |
| 6.79 | 0.01 | 2 | No | No | ken and barbie (ken) | Transcription factor, loss of genitalia |
| 6.92 | 0.03 | 2 | Yes | No | knickkopf (knk) | Embryonic blimp phenotype |
| 9.89 | 0.01 | 2 | No | No | vrille (vri) | Wing hair, vein, marginal row phenotypes |
| 12.91 | 0.03 | 2 | Yes | Yes | CG7214 | Cuticle protein |
| 13.35 | 0.03 | 2 | Yes | No | CG12045 | Cuticle protein |
| 13.45 | 0.00 | 2 | Yes | No | CG9295 | Cuticle protein |
| 13.50 | 0.00 | 2 | No | No | Buffy | Regulator of apoptosis |
| 16.66 | 0.05 | 2 | Yes | Yes | dusky (dy) | Small dark wing phenotype, related to m |
| 19.33 | 0.03 | 2 | Yes | Yes | CG6458 | Structural constituent of larval cuticle |
| 25.65 | 0.01 | 2 | No | No | osi11 | Member of osirus family |
| 34.39 | 0.04 | 2 | Yes | Yes | Myosin heavy chain (Mhc) | Muscle protein |
| 41.52 | 0.00 | 2 | Yes | Yes | osi3 | Member of osirus family |
| 41.95 | 0.02 | 2 | Yes | Yes | CG1869 | Chitinase |
| 57.63 | 0.00 | 2 | Yes | Yes | Drip | Aquaporin-like |
| 68.85 | 0.02 | 2 | Yes | Yes | CG17355 | Protease inhibitor |
| 117.91 | 0.00 | 2 | Yes | Yes | CG15013 | Related to dy and m |
| 118.20 | 0.00 | 2 | Yes | Yes | osi12 | Member of osirus family |