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. 2006 May 3;103(20):7583–7588. doi: 10.1073/pnas.0511108103

Table 1.

Caspase-3 substrates identified by using CLiPS with a 6-mer library

Substrate P5 P4 P3 P2 P1 P1′ P2′ P3′ P4′ Conversion
Canonical q D E V D G g q s 0.95 ± 0.03
CS 2.7 s D G V D G W g g 0.95
CS 2.14 (4)* s D V V D G W g g 0.94 ± 0.03
CS 2.23 s D G V D G V g g 0.93
CS 2.11 g g s L D T W T A 0.81
CS 2.20 (2) L D T V D R g g q 0.79 ± 0.01
CS 2.59 s D S T D S G g g 0.79
CS 2.1 g s Q V D G V G g 0.75
CS 2.26 g s E V D G R H g 0.75
CS 2.56 s T E V D G P g g 0.75
CS 2.47 g s E V D G G W g 0.74
CS 2.10 T D G T D G g g q 0.72
CS 2.62 Q D G V D T g g q 0.70
CS 2.2 g s E V D G S R g 0.67
CS 2.4 g s Y V D G V V g 0.64
CS 2.33 S D F V D R V g g 0.59
CS 2.36 (2) g s M V D G A M g 0.56 ± 0.05
Consensus X D X V D G

*Number of clones with identical sequence.