Table 2.

Enteropeptidase substrates identified by using CLiPS with a 6-mer library

Substrate	P5	P4	P3	P2	P1	P1′	P2′	P3′	P4′	Conversion
Canonical	D	D	D	D	K	g	g	q	s	0.15 ± 0.08
EP 4.3	s	S	G	D	R	M	W	g	g	0.97 ± 0.01
EP 4.6	s	S	G	E	R	M	M	G	g	0.93 ± 0.03
EP 4.7	g	s	D	D	R	R	A	G	g	0.91 ± 0.03
EP 4.8	V	R	D	Y	R	M	g	g	q	0.87 ± 0.04
EP 3.6	g	s	s	D	R	A	R	V	W	0.86 ± 0.05
EP 4.1	s	V	D	Y	R	F	L	g	s	0.84 ± 0.02
EP 4.2	M	H	G	E	R	M	g	g	s	0.84 ± 0.02
EP 2.5	M	S	G	E	R	M	g	g	s	0.84 ± 0.03
EP 4.10	g	s	S	E	R	A	A	A	G	0.78 ± 0.02
EP 4.9	s	V	L	D	R	W	M	g	g	0.72 ± 0.05
EP 4.4	s	E	Y	D	R	Q	L	g	s	0.71 ± 0.01
EP 2.2	A	A	V	E	R	W	g	g	s	0.69 ± 0.14
Consensus		X	X	D/E	R	M	X