TABLE 2.
Multipoint and single-point NPLall statistic for linkage analysis with different markers and numbers of families
| Multipoint
|
Single-point
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Markers/families | Position (cM) | Marker | NPLall | P-value | Infoall | NPLall | P-value | Infoall |
| 6 markers/27 families | 79.6 | SW1621 | 2.57 | 0.006 | 0.47 | 2.14 | 0.018 | 0.38 |
| 93.9 | S0155 | 1.97 | 0.027 | 0.65 | 1.71 | 0.046 | 0.61 | |
| 14 markers/27 families | 67.6 | SW2185 | 1.13 | 0.131 | 0.66 | −0.14 | 0.548 | 0.31 |
| 79.6 | SW1621 | 2.39 | 0.01 | 0.74 | 1.95 | 0.028 | 0.35 | |
| 86.4 | SWR982 | 1.72 | 0.046 | 0.88 | 0.47 | 0.316 | 0.50 | |
| 91.1 | S0155 | 1.72 | 0.046 | 0.83 | 1.83 | 0.036 | 0.61 | |
| 14 markers/8 new families | 67.6 | SW2185 | 2.61 | 0.006 | 0.91 | 1.68 | 0.044 | 0.62 |
| 79.6 | SW1621 | 0.44 | 0.363 | 0.54 | −0.15 | 0.586 | 0.45 | |
| 86.4 | SWR982 | 1.43 | 0.086 | 0.85 | 0.81 | 0.185 | 0.56 | |
| 93.9 | S0155 | 1.01 | 0.156 | 0.68 | 0.16 | 0.402 | 0.22 | |
| 14 markers/35 families | 67.6 | SW2185 | 2.05 | 0.022 | 0.71 | 0.71 | 0.236 | 0.36 |
| 79.6 | SW1621 | 2.00 | 0.025 | 0.73 | 1.40 | 0.083 | 0.35 | |
| 86.4 | SWR982 | 2.00 | 0.025 | 0.88 | 0.78 | 0.287 | 0.50 | |
| 93.9 | S0155 | 1.79 | 0.039 | 0.80 | 1.44 | 0.077 | 0.51 | |
Marker positions on SSC 1 are given in centimorgans with the exact P-value for the NPL statistic and information content (Infoall).