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. 2006 Mar 20;2:9. doi: 10.1186/1744-8069-2-9

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Copyright © 2006 Zhang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of two PP2A inhibitors, OA and fostriecin, on the reduced exploratory activity of rats initiated by capsaicin injection during a consecutive period of 45 minutes (9 intervals, 5 min/interval). Compared to the rats in the ACSF-pretreated group (n = 7), the rats with either OA (20 nM, n = 7) or fostriecin (30 nM, n = 5) pretreatment displayed significantly decreased exploratory activity, including a decreased number of photobeams broken (A), shortened distance traveled (B), decreased active time (C), increased resting time (D), shortened rearing time (E), and decreased number of rearing events (F). *p < 0.05.