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Transcription factors binding profiles to NFκB-regulated ISG promoters in WT and NFκB-KO fibroblasts. ChIP assays were performed on extracts from control and IFN-treated MEFs using the indicated antibodies for precipitation and various primers that targeted specific regions in the Ifi47 (A), Tap1 (B), and Mx1 (C) promoters (see methods). Similar results were obtained in at least three independent experiments.
