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. Author manuscript; available in PMC: 2006 May 4.
Published in final edited form as: Nature. 2005 Oct 13;437(7061):1027–1031. doi: 10.1038/nature04050

Figure 4.

Figure 4

A critical level of GABAergic inhibition regulates LTP induction in dopamine neurons. a, The effects of partial blocking of GABAA receptor with bicuculline (BMI, 0.3 and 1 μM) on LTP induction in 5-7 d saline-treated rats. Scales: 5 mV, 50 ms. b, The effects of enhancing GABAA receptor activation with diazepam (DIA, 0.1 and 1 μM) on LTP induction in 5-7 d cocaine-treated rats. Scales: 5 mV, 50 ms. c, Summary graph showing concentration-dependent effects of bicuculline and diazepam on LTP induction in saline- and cocaine-treated rats. Error bars, s.e.m.

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