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. Author manuscript; available in PMC: 2006 May 4.
Published in final edited form as: Nature. 2005 Oct 13;437(7061):1027–1031. doi: 10.1038/nature04050

Figure 5.

Figure 5

Comparison of LTP induced by two different protocols and cocaine-induced changes in the AMPAR/NMDAR ratio. a, Effects of spike-timing and steady-depolarization pairing protocols on the amplitude of EPSPs (spike-timing, same data of Fig.2c but averaged at 5 min interval) and EPSCs (steady depolarization) for 1 d saline-treated rats (n = 7). c, Examples of total, AMPAR and NMDAR-mediated EPSCs in slices from 1 d saline- and cocaine-injected rats. Scales: 50 pA, 15 ms. c, Summary of mean AMPAR/NMDAR ratios obtained by the experimenters who were either “blind” or “nonblind” to the treatment history of the rats. * p < 0.05, t-test. Error bars, s.e.m.

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