. 2001 Jan 2;98(1):235–240. doi: 10.1073/pnas.98.1.235

Table 3.

The ALR genome provides dominant protection from the adoptive transfer of diabetes by NOD.AI4 bone marrow

Marrow donor	Recipient (1,200 rad treated)	IDDM 20 weeks reconstitution, %	Insulitis index (1 = max)	Splenocytes, %
Marrow donor	Recipient (1,200 rad treated)	IDDM 20 weeks reconstitution, %	Insulitis index (1 = max)	CD8⁺	CD4⁺	TgCD8⁺	TgCD4⁺
NOD.AI4	NOD	100	1.00	15.4 ± 1^*	26.1 ± 3^*	70 ± 5^*	87 ± 6^*
NOD.AI4	ALR	0	0.10	7.2 ± 1^{^†}	17.2 ± 1^{^†}	99 ± 1^{^†}	62 ± 6^{^†}
NOD.AI4	(ALR × NOD)F₁	0	0.15	8.6 ± 1^{^†}	19.0 ± 1^{^†}	92 ± 3^{^†}	28 ± 1^{^‡}
NOD.AI4	(NOD × ALR)F₁	0	0.20	7.4 ± 2^{^†}	19.0 ± 2^{^†}	72 ± 1^*	21 ± 1^{^§}

Data shown are mean ± SD. n = 5 for all experiments. Means with different symbols (*, †, ‡) within a column are significantly different at P < 0.05. Means with the same symbol are not significantly different.