Table 1.

Very long chain fatty acid values and clinical features of affected family members

Case	II-4	II-3	II-2	IV-1	IV-2	Normal values (μmol/L)
C26	2.15	2.21	4.48	3.43	2.98	0.33-1.39
C26:C22 ratio	0.055	0.059	0.066	0.070	0.061	<0.030
C24:C22 ratio	1.49	1.12	1.40	1.33	1.27	0.32-1.07
Age at onset (years)	31	38	40	2.5	2.0
Adrenal failure	Yes	Yes	Yes	Yes	Yes
Cerebral involvement (symptomatic)	Yes	No	No	Yes	No