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(a) Metaphase showing fluorescence ISH with the HPP1 probe. Normal male chromosomes stained with 4′,6-diamidino-2-phenylindole. Hybridization sites on chromosome 2 are indicated; 86% of the signal was at 2q32.3. (b) LOH analysis using the Microsatellite marker CT23i. Samples displaying LOH are indicated (*). N, normal mucosa; T, tumor; P, polyp DNA.
