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. 1980 Apr;39(4):511–517.

Comparative studies of a monoclonal IgG lambda and two IgE kappa components from an individual patient: evidence for shared idiotypic determinants between the two IgE proteins but not with the IgG lambda protein.

G G Cornwell 3rd, T E Michaelsen, W H Sanders
PMCID: PMC1458024  PMID: 6155327

Abstract

An IgG lambda and two IgE kappa proteins were isolated from the serum of a patient (DB) with anaemia associated with myelofibrosis. Idiotype-specific antisera produced against the three proteins were studied by precipitation in double immunodiffusion and by enzyme-linked immunosorbent assay (ELISA) and indicated that the two IgE kappa components shared idiotypic determinants while the IgG lambda protein did not show any cross-idiotypic reaction. The idiotypic determinants of the three proteins were not present in pooled normal serum, normal IgG, normal IgE or IgE from a patient with multiple myeloma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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