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Lung cytokine appearance after Ad/hIL-10 and Ad/vIL-10 instillation. Lung TNF-α levels were minimal after Ad/IL-10 instillation, but there was a trend toward increased TNF-α production in the lungs of mice receiving Ad/hIL-10 (A). Similarly, IL-1α (B) and myeloperoxidase (C) were increased significantly in the lungs of mice receiving Ad/hIL-10 as compared with those receiving Ad/vIL-10 (P < 0.001).
