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. 1980 Dec;41(4):899–902.

Comparative aspects of the transport of immunoglobulin A from blood to bile.

J G Hall, L A Gyure, A W Payne
PMCID: PMC1458304  PMID: 7461715

Abstract

Polymeric and monomeric human IgA were isolated from the sera of patients with IgA myeloma; rat IgA polymer, monomer and IgG2 were isolated from the ascitic fluid or sera of Lou/Wsl rats bearing appropriate myelomata. The purified Ig preparations were labelled with 125I and injected intravenously into rats, rabbits, guinea-pigs or sheep that had had a cannula inserted into the common bile duct so that their bile could be collected quantitatively. Rats and rabbits transported 30% of the injected dose of both IgA polymers, but no other type of immunoglobulin, from blood to bile within 5--7 h. Sheep and guinea-pigs were unable to transport any of the immunoglobulin preparations from blood to bile, even though the injected material remained circulating in the blood.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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