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. 2006 Apr 3;103(15):5723–5728. doi: 10.1073/pnas.0511225103

Fig. 3.

Fig. 3.

Body weight changes and AA levels in the plasma, livers, and kidneys of SMP30Y− and SMP30Y+ mice. SMP30Y− and SMP30Y+ mice, six each, were weaned at 30 days of age and fed autoclaved mouse chow (containing ≈55 mg of AA per kg) for 10 days; then, they were fed a vitamin C-deficient diet until all SMP30Y− animals were dead. (A) Body weight changes of SMP30Y− (pink circles) and SMP30Y+ (green circles) mice. One SMP30Y− mouse died after 37 days (indicated by star), and the others died after 106–135 days of consuming the vitamin C-deficient diet. (B–D) Blood was taken from all tested animals (six WT and five knockout mice) after 106 days of this diet, and AA levels in the plasma (B) were measured. All mice were killed after 136 days of receiving the deficient diet, and AA levels in the liver (C) and kidney (D) were measured. Except for blood, all specimens of SMP30Y− mice were taken after death. Values are expressed as mean ± SEM of five or six animals.