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Gain/amplification of Kras2 and Myc in mouse PDAC
| Genotype | Kras2, % | Myc, % |
|---|---|---|
| p53lox/lox (n = 10) | 40 | 30 |
| p53lox/+ (n = 6) | 17 | 33 |
| All p53 (n = 16) | 31 | 31 |
| p16Ink4a/p19Arf lox/lox (n = 16) | 81 | 6 |
| p16Ink4a/p19Arf lox/+ (n = 8) | 63 | 13 |
| All p16Ink4a/p19Arf (n = 24) | 75 | 8 |
