Severe reduction in proliferation in the postnatal orJ central retina. The effect of Chx10 loss on central retinal proliferation was assessed by counting the proportion of PH3-positive mitotic cells at three time points. By P3, proliferation in the central orJ retina had decreased dramatically. Error bars represent SD. Asterisks indicate significant difference between WT and orJ (P ≤ 0.03). DP, dorsal peripheral; DM, dorsal medial; DC, dorsal central; VC, ventral central; VM, ventral medial; VP, ventral peripheral.