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. 2006 Mar 20;103(13):5060–5065. doi: 10.1073/pnas.0511167103

Fig. 1.

Fig. 1.

Galectin-3 expression is up-regulated in human liver fibrosis. (a) Galectin-3 expression in normal human liver. (b) Galectin-3 in cirrhosis secondary to hepatitis C infection. (Scale bar: 400 μm.) Galectin-3 expression is temporally and spatially related to fibrosis in a reversible rat model of liver fibrosis. (c Upper) Collagen stained with PSR. (Scale bar: 100 μm.) (c Lower) Galectin-3 immunohistochemistry. (Scale bar: 200 μm.) (Left) Control (olive oil vehicle only). (Middle) Peak fibrosis in rat liver after 12 weeks of twice weekly i.p. CCL4. (Right) Resolution, 24 weeks after cessation of CCL4-induced liver injury.