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. 2006 Mar 20;103(13):5060–5065. doi: 10.1073/pnas.0511167103

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© 2006 by The National Academy of Sciences of the USA

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Fig. 5. — Galectin-3 SiRNA-mediated inhibition of HSC activation in vivo. (a) Galectin-3 and α-SMA staining of liver tissue harvested 3 days after CCL₄ injury (n = 6 mice in each group). Mice received saline (PBS), control duplex (CD), or Galectin-3 siRNA (siRNA). (Scale bar: 200 μm.) (b Left) Real-time PCR quantitation of Galectin-3 expression in liver homogenates 3 days after CCL₄ injury. ∗∗, P < 0.01 compared with CD. (b Right) Real-time PCR analysis of α-SMA expression in liver homogenates 3 days after CCL₄ injury. ∗∗, P < 0.01 compared with CD.