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Islet-specific expression of the ΔNIκBα gene in transgenic mice. Lysates from tissues (+) (lanes 3–5) or from isolated islets from double-transgenic mice treated with Dox for 3 days (+) (lane 2) or untreated (−) (lane 1) were tested for ΔNIκBα expression by Western blot analysis by using antibodies against the C-terminal domain of IkBα.
