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. 2006 Apr 10;103(16):6287–6292. doi: 10.1073/pnas.0600158103

Fig. 5.

Fig. 5.

Summary of the melanosome transport assay in 5-day zebrafish embryos injected with trim32 MO with and without mRNA rescue. Control MO- and trim32 MO-injected embryos were observed for melanosome transport response time after epinephrine treatment. Embryos treated with trim32 MO alone showed an average response time of 178 s compared with an average 94-s response time for embryos treated with the control MO (P < 0.0001). Both WT human TRIM32 (103 s) and the D487N allele mRNA (103 s) rescued the melanosome transport defect (not significantly different from controls). The P130S allele (158 s) failed to rescue the transport defect (P < 0.0001 compared with controls).