Fig. 5.

Expression of HoxA5, Gpc4 and Tbx15 in s.c. and visceral adipose tissue in humans are correlated with adiposity and fat distribution. One hundred ninety-eight subjects (99 males and 99 females) ranging from lean to obese with variable BMI (A) and fat distribution (WHR) (B) were subjected to visceral (Vis, open bars) and s.c. (SC, filled bars) adipose tissue biopsies. Gene expression of HoxA5, Gpc4, and Tbx15 was assessed in both fat depots by qPCR as described in Materials and Methods. Correlation significances were determined by using statview software either as linear correlations or, in the case of nonlinear correlations, by exponential or lowest curve fitting.