Baseline time course of sigma (10–15 Hz; Upper) and delta (1–4 Hz; Lower) EEG activity in NREMS. Values represent mean absolute values (±1 SEM) calculated over 15- and 5-NREMS-time percentiles in the light and dark periods, respectively. Large genotype and sex effects were present for both frequency bands [three-way ANOVA (factors genotype, sex, and time), P < 0.0001; except the genotype for delta, P = 0.51), and sex affected the genotype effect (interaction P < 0.0001). The time-dependent changes in both variables did not differ among groups. Colored bars at the bottom indicate intervals in which EEG power differed among groups (P < 0.05, t tests).