Table 1.
Sleep time during baseline
| NREMS | REMS | |||||
|---|---|---|---|---|---|---|
| 12 h light | 12 h dark | 24 h | 12 h light | 12 h dark | 24 h | |
| WT females | 404 ± 6 | 132 ± 10 | 536 ± 13 | 68 ± 4 | 16 ± 3 | 85 ± 6 |
| WT males | 416 ± 7 | 149 ± 11 | 565 ± 12 | 68 ± 3 | 18 ± 2 | 86 ± 4 |
| KO females | 403 ± 7 | 94 ± 15* | 496 ± 12* | 74 ± 3 | 13 ± 3 | 87 ± 3 |
| KO males | 414 ± 6 | 109 ± 13* | 523 ± 10* | 67 ± 3 | 12 ± 2* | 79 ± 4 |
| Two-way ANOVA | ||||||
| Genotype | 0.77 | 0.0041 | 0.0015 | 0.41 | 0.053 | 0.64 |
| Sex | 0.10 | 0.20 | 0.022 | 0.21 | 0.85 | 0.39 |
| Interaction | 0.96 | 0.94 | 0.92 | 0.31 | 0.52 | 0.27 |
Mean (±SEM) minutes of sleep obtained over 2 baseline days. P values resulting from two-way ANOVAs with genotype and sex factors are indicated.
*Significant genotype differences (P < 0.05, t tests).