Table 2.

Activating effect of agonists on Time to Peak

Assay System N-PRP plus	TTP (minutes) mean ± SD
	B	C	D	E	F	G	H
	Saline	rFVIIa 5 μg/mL	p value B vs C	rFVIIa 2.6 μg/mL	P value B vs E	rFVIIa 0.5 μg/mL	P value B vs G
1. Saline	21.8 ± 3.9	14.3 ± 3.1	<0.001	15.1 ± 3.2	<0.001	16.5 ± 3.2	<0.001
2. ADP 2 μM	16.8 ± 3.5	13.4 ± 2.8	<0.01	13.8 ± 2.4	<0.01	13.9 ± 3.0	<0.01
3. Col 0.5 μg/mL	16,6 ± 3.4	12.5 ± 3.2	<0.05	13.5 ± 3.1	<0.01	13.3 ± 3.1	<0.01
4. AA 0.625 mmol/L	13.5 ± 2.8	12.0 ± 2.2	NS	12.1 ± 2.6	NS	12.2 ± 2.5	NS
5. AA 0.125 mmol/L	14.6 ± 3.5	12.7 ± 2.6	NS	13.1 ± 2.7	NS	12.9 ± 2.5	NS

Parameters of TG in PRP from 29 normal volunteers. Effect of ADP, collagen (Col); sodium arachidonate (AA) and rFVIIa at different concentrations.

Column B:1 vs 2 to 5 p < 0.001 for all. Column C 1 vs 4 p = 0.05

Column E: 1 vs 4, 5 p < 0.01 and <0.05; Column G: 1 vs 2 to 5 p < 0.01.