Table 3.

Activating effect of agonists on Peak of TG (PTG).

Assay System N-PRP plus	PTG (nmol/L) mean ± SD
	B	C	D	E	F	G	H
	Saline	rFVIIa 5 μg/mL	p value B vs C	rFVIIa 2.6 μg/mL	P value B vs E	rFVIIa 0.5 μg/mL	P value B vs G
1. Saline	97 ± 36	160 ± 36	<0.001	151 ± 42	<0.001	189 ± 42	<0.001
2. ADP 2 μM	156 ± 50	178 ± 49	NS	167 ± 45	NS	214 ± 70	<0.01
3. Col 0.5 μg/mL	158 ± 60	180 ± 45	NS	174 ± 46	NS	215 ± 63	<0.01
4. AA 0.625 mmol/L	160 ± 43	164 ± 42	NS	172 ± 49	NS	204 ± 59	<0.01
5. AA 0.125 mmol/L	191 ± 52	193 ± 52	NS	184 ± 49	NS	222 ± 69	NS

Parameters of TG in PRP from 29 normal volunteers. Effect of ADP, collagen (Col); sodium arachidonate (AA) and rFVIIa at different concentrations.

Column B:1 vs 2 to 5 p < 0.001 for all Column C 1 vs 5 p < 0.01, Column E: 1 vs 5 p < 0.05