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The application accuracy was monitored intraoperatively using as a reference point a 1 mm burr hole (b) drilled into the exposed bone margin (a) directly after craniotomy. The Cartesian coordinates of this reference point were used to calculate the intraoperative Position Error (PE = (Δsagittal 2 + Δcoronal 2 + Δaxial 2)1/2) in mm.
