Table 1.
Clinical data of 40 cases
| Patient No. | appl. type & procedure | gender & age | diagnosis | localization | CT/MRI-data | FRE (mm) |
| 1 | A | m 28 y | glioma WHO III | left frontal | MRI | 1,74 |
| 2 | A | f 72 y | glioblastoma | left frontal | MRI | 1,17 |
| 3 | A | f 52 y | metastasis | right occipital | MRI | 1,28 |
| 4 | A | f 68 y | glioma WHO III | right parietal | MRI | 2,16 |
| 5 | A | f 81 y | glioblastoma | left parietal | MRI | 1,57 |
| 6 | A | f 56 y | metastasis | left temporal | MRI | 1,65 |
| 7 | A | f 73 y | metastasis | right frontal | MRI | 1,36 |
| 8 | A | m 30 y | metastasis | left temporal | MRI | 0,91 |
| 9 | A | m 61 y | glioblastoma | left parietal | MRI | 1,37 |
| 10 | A | m 60 y | glioblastoma | left parietal | MRI | 1,84 |
| 11 | B1 (MLL) | f 63 y | metastasis | left frontal/left parietal | MRI | 2,11 |
| 12 | B1 (MLL) | m 63 y | metastasis | right frontal/left temporal | MRI | 1,24 |
| 13 | B1 (MLL) | f 48 y | metastasis | left frontal/right frontal | MRI | 1,85 |
| 14 | B1 (MLL) | f 66 y | metastasis | left frontal/left occipital | MRI | 1,44 |
| 15 | B1 (SBP) | m 49 y | prim. bone tumour | skull base + orbita | CT | 1,17 |
| 16 | B2 (MLL) | f 67 y | metastasis | right frontal/right parietal | MRI | 1,41 |
| 17 | B2 (MLL) | f 68 y | metastasis | right frontal/right parietal | MRI | 1,33 |
| 18 | B2 (SBP) | m 54 y | meningioma | skull base + orbita | CT | 1,24 |
| 19 | B2 (SBP) | f 52 y | meningioma | skull base + orbita | CT | 1,68 |
| 20 | B2 (SBP) | m 67 y | prim. bone tumour | skull base + orbita | CT | 2,05 |
| 21 | C1 (BHP) | f 18 y | astrocytoma WHO II | left temporal | MRI | 2,54 |
| 22 | C1 (BHP) | m 56 y | astrocytoma WHO III | left temporal | MRI | 1,87 |
| 23 | C1 (BHP) | m 27 y | lymphoma | right parietal | MRI | 1,57 |
| 24 | C1 (BHP) | m 61 y | glioblastoma | left frontal | CT | 1,21 |
| 25 | C1 (BHP) | m 64 y | lymphoma | left temporal | MRI | 1,17 |
| 26 | C1 (BHP) | m 46 y | lymphoma | right temporal | MRI | 1,30 |
| 27 | C1 (BHP) | m 65 y | glioma WHO III | left temporal | MRI | 2,98 |
| 28 | C1 (TNA) | m 35 y | fibrous dysplasia | skull base | CT | 1,32 |
| 29 | C1 (TNA) | f 62 y | paraganglioma | right Fossa pterygopalatina | MRI | 2.12 |
| 30 | C1 (TNA) | m 54 y | fibrous dysplasia | skull base | CT | 1,24 |
| 31 | C2 (BHP) | m 64 y | lymphoma | left frontal | CT | 1,33 |
| 32 | C2 (BHP) | f 51 y | glioblastoma | left frontal | MRI | 1,54 |
| 33 | C2 (BHP) | m 54 y | astrocytoma WHO III | right frontal | MRI | 1,87 |
| 34 | C2 (BHP) | m 48 y | astrocytoma WHO II | left frontal | MRI | 2,27 |
| 35 | C2 (BHP) | m 65 y | metastasis | left frontal | CT | 2,24 |
| 36 | C2 (BHP) | f 70 y | glioblastoma | left temporal | MRI | 1,56 |
| 37 | C2 (AWC) | f 66 y | metastasis | left frontal | MRI | 1,08 |
| 38 | C2 (AWC) | m 26 y | glioma WHO III | left fronto-temporal | MRI | 1,87 |
| 39 | C2 (AWC) | f 63 y | glioma WHO III | left temporal | MRI | 2,23 |
| 40 | C2 (AWC) | m 56 y | glioma WHO III | left temporal | MRI | 1,51 |
m = male; f = female; y = years; FRE = Fiducial Registration Error
Type A (control group) = 3-point-pin fixation; no DRF
Type B1 = 3-point-pin fixation; oral DRF; Type B2 = 3-point-pin fixation; retroauricular DRF
Type C1 = unfixed head; oral DRF; Type C2 = unfixed head; retroauricular DRF
MLL = multilocular lesion; BHP = burr hole procedure for biopsy/endoscopy; SBP = Skull base procedure; TNA = transnasal approach; AWC = awake craniotomy