Table 2.
age, sex, breed | onset of symptoms | clinical | family affected | legs | patella | heart | PA | aorta | eyes | other tissues | ultrasound | |
1 | 18 mo, F thoro | 6 mos | rear legs | no | 4 mild | ND | ND | ND | + | ND | nuchal+ | ND |
2 | 5 y, M Han | 16 mo | forelimbs | no | 4 severe | ND | Cor + | ND | + | R eye + | nuchal+ | front SLs |
3 | 5 y, F, Appal | 6 mos | four | sire | 4 severe | yes | cor N | ND | + | both+ | nuchal, lung + | 2/2 hind SLs |
4 | 8 y, M thoro | 6 yr | rear legs | sire sudden death | 4 mild | ND | ND | ND | + | - | nuchal+ | rear legs |
5 | 16 y, M, Arab | unknown | years | no | 4 mild | ND | valve+ | ND | + | - | - | ND |
6 | 18 y, F quarter, | unknown | rear legs, lung sounds | no | 4 mild | ND | cor | ND | + | both+ | nuchal, lung + | rear legs |
Age: age at necropsy; ND: not done; legs: SDFT, DDFT and SL; cor: coronary artery; PA: pulmonary artery; nuchal: nuchal ligament; Han: Hanovarian; Appal: Appaloosa; thoro: thoroughbred
Mild, mod (moderate), severe: describes the average severity of pathology in examined leg tendons and ligaments; +: accumulation of proteoglycans in other tissues; -: no proteoglycan accumulation