Table 1.

Bovine experimental groups

BColl/CFA (n = 4 for comparison to 4-week groups) (n = 4 for comparison to 12-week groups)	Positive control; bovine collagen with complete Freund's adjuvant, euthanized 3 weeks after injection
BColl/IFA (n = 4 for comparison to 4-week groups) (n = 4 for comparison to 12-week groups)	Positive control; bovine collagen with incomplete Freund's adjuvant, euthanized 3 weeks after injection
Bo-UP-4 (n = 7)	Unprocessed bovine graft, 4 weeks implantation
Bo-P-4 (n = 8)	Photooxidized bovine graft, 4 weeks implantation
Bo-S-4 (n = 4)	Negative control; sham operation, euthanized 4 weeks post-op
Bo-UP-12 (n = 8)	Unprocessed bovine graft, 12 weeks implantation
Bo-P-12 (n = 8)	Photooxidized bovine graft, 12 weeks implantation
Bo-S-12 (n = 4)	Negative control; sham operation, euthanized 12 weeks post-op

B or Bo = bovine; UP = unprocessed; P = photooxidized; S = sham