Table 2.
Estimates of the Impact of HAART on the Mean Change in QOL Scores from Propensity-Score Matched Pattern Mixture Models.
| Model 1a | Model 2b | Model 3c | Model 4d | Model 5e | |||||||
| Effect | P-Value | Effect | P-Value | Effect | P-Value | Effect | P-Value | Effect | P-Value | ||
| Summary QOL Score | Short-Term HAART Effect | 2.07 | 0.11 | 2.25 | 0.07 | 2.26 | 0.07 | 2.24 | 0.08 | 3.25 | 0.02 |
| Change per 6 months | -0.30 | 0.01 | -0.30 | 0.01 | -0.21 | 0.08 | -0.29 | 0.02 | -0.29 | 0.01 | |
| Physical functioning | Short-Term HAART Effect | 0.71 | 0.70 | 0.72 | 0.70 | 0.83 | 0.66 | 0.15 | 0.94 | 1.86 | 0.35 |
| Change per 6 months | -0.39 | 0.02 | -0.39 | 0.02 | -0.28 | 0.14 | -0.36 | 0.07 | -0.30 | 0.10 | |
| Role functioning | Short-Term HAART Effect | 5.08 | 0.01 | 5.40 | 0.01 | 5.46 | 0.01 | 5.98 | 0.01 | 6.99 | 0.00 |
| Change per 6 months | -0.40 | 0.04 | -0.36 | 0.07 | -0.34 | 0.11 | -0.47 | 0.03 | -0.45 | 0.04 | |
| Energy/fatigue | Short-Term HAART Effect | -0.09 | 0.96 | 0.37 | 0.83 | 0.32 | 0.86 | 0.43 | 0.81 | 1.24 | 0.51 |
| Change per 6 months | -0.30 | 0.06 | -0.31 | 0.05 | -0.19 | 0.28 | -0.21 | 0.24 | -0.26 | 0.13 | |
| Social functioning | Short-Term HAART Effect | 4.33 | 0.01 | 4.96 | 0.00 | 4.90 | 0.01 | 5.03 | 0.01 | 5.74 | 0.00 |
| Change per 6 months | -0.22 | 0.19 | -0.19 | 0.25 | -0.13 | 0.47 | -0.19 | 0.30 | -0.19 | 0.30 | |
| Cognitive functioning | Short-Term HAART Effect | 2.58 | 0.08 | 3.51 | 0.02 | 3.46 | 0.02 | 3.48 | 0.03 | 3.59 | 0.03 |
| Change per 6 months | -0.08 | 0.57 | -0.07 | 0.61 | 0.07 | 0.64 | 0.04 | 0.78 | -0.04 | 0.82 | |
| Pain | Short-Term HAART Effect | 4.53 | 0.01 | 4.33 | 0.02 | 4.33 | 0.02 | 4.65 | 0.02 | 6.73 | 0.00 |
| Change per 6 months | -0.25 | 0.15 | -0.26 | 0.14 | -0.10 | 0.58 | -0.21 | 0.29 | -0.19 | 0.32 | |
| Emotional well-being | Short-Term HAART Effect | 2.38 | 0.12 | 2.46 | 0.12 | 2.47 | 0.12 | 2.45 | 0.12 | 2.05 | 0.20 |
| Change per 6 months | -0.16 | 0.25 | -0.17 | 0.23 | -0.18 | 0.23 | -0.26 | 0.11 | -0.30 | 0.05 | |
| Health perception | Short-Term HAART Effect | 2.60 | 0.10 | 3.05 | 0.06 | 3.04 | 0.06 | 3.43 | 0.04 | 3.67 | 0.03 |
| Change per 6 months | -0.49 | 0.00 | -0.49 | 0.00 | -0.45 | 0.00 | -0.50 | 0.00 | -0.53 | 0.00 | |
| Perceived health index | Short-Term HAART Effect | 4.25 | 0.00 | 4.79 | 0.00 | 4.67 | 0.00 | 4.65 | 0.00 | 4.87 | 0.00 |
| Change per 6 months | -0.08 | 0.86 | -0.09 | 0.87 | -0.11 | 0.87 | -0.11 | 0.84 | -0.09 | 0.83 | |
a Model 1: Model includes an intercept, an indicator of HAART or HAART-naïve group (Short-Term HAART Effect) and the time from index visit (Change per 6 months).
b Model 2: Model 1 + age, ethnicity and education level.
c Model 3: Model 2 + income, employment and health insurance.
d Model 4: Model 3+ CD4+ cell counts and viral load.
e Model 5: Model 4+ number of symptoms, outpatient visits, hospitalizations and medication, AIDS history and clinical depression. Interactions between HAART and time from index visit were not statistically significant for all models.