Table 3.
Estimates of the Impact of HAART on the Mean Change in QOL Scores from Propensity-Score Matched Pattern Mixture Models among AIDS-free Women at Matching Visits
| Model 1a | Model 2b | Model 3c | Model 4d | Model 5e | |||||||
| Effect | P-Value | Effect | P-Value | Effect | P-Value | Effect | P-Value | Effect | P-Value | ||
| Overall QOL | Short-Term HAART Effect | 0.57 | 0.70 | 0.40 | 0.79 | 0.43 | 0.78 | 0.63 | 0.69 | 1.61 | 0.35 |
| Change per 6 months | -0.24 | 0.10 | -0.26 | 0.08 | -0.19 | 0.23 | -0.26 | 0.11 | -0.20 | 0.16 | |
| Physical functioning | Short-Term HAART Effect | 0.05 | 0.98 | -0.19 | 0.94 | -0.23 | 0.92 | -0.88 | 0.73 | 0.55 | 0.83 |
| Change per 6 months | -0.27 | 0.25 | -0.28 | 0.23 | -0.26 | 0.31 | -0.37 | 0.14 | -0.25 | 0.26 | |
| Role functioning | Short-Term HAART Effect | 2.48 | 0.33 | 2.61 | 0.30 | 2.73 | 0.28 | 3.03 | 0.24 | 4.13 | 0.12 |
| Change per 6 months | -0.30 | 0.25 | -0.26 | 0.32 | -0.28 | 0.33 | -0.33 | 0.26 | -0.26 | 0.35 | |
| Energy/fatigue | Short-Term HAART Effect | -2.22 | 0.30 | -2.12 | 0.31 | -2.14 | 0.31 | -1.67 | 0.44 | -0.71 | 0.75 |
| Change per 6 months | -0.25 | 0.22 | -0.30 | 0.16 | -0.19 | 0.42 | -0.26 | 0.27 | -0.24 | 0.28 | |
| Social functioning | Short-Term HAART Effect | 3.17 | 0.12 | 3.71 | 0.08 | 3.85 | 0.08 | 4.33 | 0.05 | 5.27 | 0.02 |
| Change per 6 months | -0.17 | 0.43 | -0.16 | 0.44 | -0.08 | 0.73 | -0.09 | 0.71 | 0.01 | 0.97 | |
| Cognitive functioning | Short-Term HAART Effect | 0.86 | 0.61 | 2.21 | 0.22 | 2.23 | 0.22 | 2.54 | 0.16 | 2.38 | 0.22 |
| Change per 6 months | -0.13 | 0.46 | -0.11 | 0.52 | -0.05 | 0.79 | -0.06 | 0.76 | -0.11 | 0.54 | |
| Pain | Short-Term HAART Effect | 3.25 | 0.13 | 2.53 | 0.24 | 2.69 | 0.21 | 3.46 | 0.13 | 5.96 | 0.02 |
| Change per 6 months | -0.21 | 0.36 | -0.26 | 0.28 | -0.11 | 0.67 | -0.17 | 0.52 | -0.11 | 0.66 | |
| Emotional well-being | Short-Term HAART Effect | 1.56 | 0.40 | 1.06 | 0.58 | 1.06 | 0.58 | 1.02 | 0.58 | 0.17 | 0.93 |
| Change per 6 months | -0.19 | 0.32 | -0.18 | 0.34 | -0.16 | 0.42 | -0.20 | 0.36 | -0.23 | 0.26 | |
| Health perception | Short-Term HAART Effect | 0.07 | 0.97 | 0.36 | 0.84 | 0.27 | 0.88 | 0.31 | 0.87 | 0.45 | 0.82 |
| Change per 6 months | -0.36 | 0.04 | -0.37 | 0.04 | -0.37 | 0.06 | -0.50 | 0.01 | -0.54 | 0.00 | |
| Perceived health index | Short-Term HAART Effect | 3.17 | 0.07 | 3.76 | 0.03 | 3.46 | 0.05 | 4.03 | 0.02 | 4.08 | 0.03 |
| Change per 6 months | -0.21 | 0.21 | -0.20 | 0.22 | -0.28 | 0.11 | -0.31 | 0.08 | -0.26 | 0.14 | |
a Model 1: Model includes an intercept, an indicator of HAART or HAART-naïve group (Short-Term HAART Effect) and the time from index visit (Change per 6 months).
b Model 2: Model 1 + age, ethnicity and education level.
c Model 3: Model 2 + income, employment and health insurance.
d Model 4: Model 3+ CD4+ cell counts and viral load.
e Model 5: Model 4+ number of symptoms, outpatient visits, hospitalizations and medication, AIDS history and clinical depression. Interactions between HAART and time from index visit were not statistically significant for all models.